The Clinical Practice of a Proprietary Natural Herbal Cream in Limb Salvage of a Patient with Multiple Co-morbidities: A Case Report
Optimizing Wound Bed and Diabetic Foot Ulcer Healing with Proprietary Natural Herbal Cream – A Case Series in the US

• Male aged 65(Egypt)
• DM 20 years
• HbA1C: 12%
• Ulcer duration : 16 weeks
• Tube consumption: 1.5
• Healing in 5 weeks
• No suture performed after surgery but only with Bonvadis

• Male aged 64 (Kingdom of Saudi Arabia)
• DM 25 years
• Ulcer duration: 3 weeks (pre-OP)
• ABI: 1
• Tube consumption: 3
• Healing in 13 weeks

• Female aged 26 (Taiwan)
• Ulcer duration: 3 months
• Tube consumption: 1
• Healing in 18 days
• 2nd and 3rd degree superficial burn wound behind the left ear
Reference: J Taiwan Soc of Plast Surg 2024;33:199~206

• The exploratory clinical trial result (N=46) showed that ON101 (applied twice daily after operation for 12 weeks) compared with the placebo has statistical significance in pigmentation, vascularity, pliability and height via Vancouver Scar Scale (VSS) measurement (P < 0.05).
• Tube consumption: < 1
Reference: Aesthet Surg J. 2023 Jan 10;sjad005.

• Female aged 67 (Taiwan)
• NPUAP grade 3
• Ulcer duration: > 4 months
• Tube consumption: < 5
• Healing in 16 weeks
Reference: Post-marketing case presented in CDS 2022

• Male aged 70 (US)
• DM 10 years
• HbA1c: 6.0%
• VLU duration: 5 weeks
• Tube consumption: 1
• Healing in 3 weeks